New route to the synthesis of P-chiral compounds

Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral ...

Predicting phosphine reactivity with one simple metric

Phosphines are among the most important ligands for transition metal catalysis. Phosphines bind to a metal and modify its structure, reactivity, and selectivity. Many of the most practiced catalytic reactions in the pharmaceutical/commodity ...

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