Related topics: new drugs · drug · clinical trials

Taking the measure of glycans

When Lorna De Leoz invited laboratories to participate in her glycomics study, she hoped for 20 responses. Instead, she was deluged by emails from around the world.

Resurrected protein reveals structure of important enzyme

To disarm toxic substances, many organisms including humans possess enzymes called flavin-containing monooxygenases (FMOs). Despite their importance, the structure of the enzymes has not been resolved, as the protein is too ...

A new way to regulate gene expression

Sometimes, unexpected research results are simply due to experimental error. Other times, it's the opposite—the scientists have uncovered a new phenomenon that reveals an even more accurate portrayal of our bodies and our ...

The truth about misinformation

In today's fast-paced digital age, information can become outdated rapidly and people must constantly update their memories. But changing our previous understanding of the news we hear or the products we use isn't always ...

Fluorescent probes offer fuller view of drug delivery in cells

Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside ...

Scientists come up with faster way to discover antibiotics

Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties. One of the discovered ...

Hook-on drugs: New delivery strategy for K-Ras disruption

"The strategy was to design the drug to be able to hook into the hole of the FTase and GGTase I, otherwise the surface of the proteins are too large and slippery," Dr. Junko Ohkanda of Shinshu University explains her strategy ...

New cyclization reactions for synthesizing macrocyclic drug leads

Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study is published in Science ...

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Pharmaceutical industry

The pharmaceutical industry develops, produces, and markets drugs licensed for use as medications. Pharmaceutical companies can deal in generic and/or brand medications. They are subject to a variety of laws and regulations regarding the patenting, testing and marketing of drugs.

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