A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power ...
Biochemistry
Aug 23, 2023
0
78
The formation of peptide bonds—the chemical bond between amino acids—in protein synthesis is one of the most important biochemical reaction steps. Without the development of structurally and catalytically active polymers, ...
Materials Science
Dec 13, 2021
0
8
A multi-enzyme platform is developed for sequence-unconstrained traceless protein synthesis and modification with either synthetic peptides or recombinant proteins, according to a new study out of Chinese Academy of Sciences ...
Biochemistry
Oct 22, 2021
0
23
Micrometer-sized gel drops can provide the extracellular architecture needed for cells to grow and proliferate. The cell-carrying gels, made of self-assembling ultrashort peptides that form supportive nanofiber networks, ...
Materials Science
Aug 9, 2021
0
455
In an important step during the early evolution of life on Earth, the formation of the amino acid cysteine delivered vital catalysts, which enabled the earliest protein molecules to form in water, according to a new study ...
Biochemistry
Nov 12, 2020
4
552
The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease. For the first time, a team led by ERC awardee Markus Muttenthaler ...
Biochemistry
Jul 7, 2020
0
6
Discovering new biological targets is a critical part of our ongoing battle against diseases. Over the years, scientists have made impressive progress towards the understanding of biological systems, constantly identifying ...
Biochemistry
Apr 18, 2019
0
60
Compounds in a fermented fish paste used as a condiment in Indonesia efficiently inhibit an enzyme involved in cholesterol synthesis, reports a study published in the Pertanika journal Tropical Agricultural Science.
Biochemistry
Sep 12, 2017
0
7
Chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have discovered a new class of molecules. This week they report in Nature Communications on their synthesis method leading to 'quasi[1]catenanes': ...
Materials Science
May 26, 2017
0
12
Ludwig Maximilian University researchers have used cryo-electron microscopic imaging to characterize the structural alterations in the bacterial ribosome that are required for induction of resistance to the antibiotic erythromycin.
Cell & Microbiology
Mar 28, 2014
0
0
