Painkillers relieve zebrafish larvae discomfort

Lynne Sneddon is a myth buster. Having debunked the fisherman's legend that fish don't feel pain, Sneddon, from the University of Liverpool, UK, has become a leading figure in the movement to reduce, replace and refine the ...

Intractable pain may find relief in tiny gold rods

A team of scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) has developed a novel technique using tiny gold rods to target pain receptors.

Treating pain by blocking the 'chili-pepper receptor'

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...

Fight or flight and the evolution of pain

Hard wired into the survival mechanisms of all animals is the perception of pain. Different stimuli, such as heat or cold, foul odors, chemicals or a blunt blow can trigger pain receptors in the body that, in the blink of ...

Do fish feel pain?

Fish do not feel pain the way humans do. That is the conclusion drawn by an international team of researchers consisting of neurobiologists, behavioural ecologists and fishery scientists. One contributor to the landmark study ...

Putting the fire out with light

Chili peppers contain an activator of heat-sensitive pain receptors. An LMU team has now converted an antagonist to the compound into a light-sensitive regulator of such receptors that can differentially modulate the effects ...

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