Treating pain by blocking the 'chili-pepper receptor'

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...

Fight or flight and the evolution of pain

Hard wired into the survival mechanisms of all animals is the perception of pain. Different stimuli, such as heat or cold, foul odors, chemicals or a blunt blow can trigger pain receptors in the body that, in the blink of ...

Do fish feel pain?

Fish do not feel pain the way humans do. That is the conclusion drawn by an international team of researchers consisting of neurobiologists, behavioural ecologists and fishery scientists. One contributor to the landmark study ...

Putting the fire out with light

Chili peppers contain an activator of heat-sensitive pain receptors. An LMU team has now converted an antagonist to the compound into a light-sensitive regulator of such receptors that can differentially modulate the effects ...

Nobel pioneers unlocked the cell door

For most of the 20th century, scientists were puzzled by how cells in our body are able to sense and react to external conditions.

Researchers block morphine's itchy side effect

Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. The opiate-associated itch is so common that even women who get epidurals for labor pain often ...

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