A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem ...
Biochemistry
Jan 31, 2011
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0
Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...
Cell & Microbiology
Jul 2, 2018
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39
Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists ...
Cell & Microbiology
Feb 11, 2021
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271
A common chemotherapy drug has been successfully delivered to cancer cells inside tiny microparticles using a method inspired by our knowledge of how the human immune system works. The drug, delivered in this way, reduced ...
Biotechnology
Sep 12, 2011
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0
Maybe you go for a leisurely walk, curl up with a good book, lift weights or reach for some comfort food when you're not feeling well or have had a particularly stressful day. Although there are myriad ways that we all outwardly ...
Plants & Animals
Nov 18, 2020
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40
A team of sciences from the RUDN Institute of Medicine has reported how reactive oxygen species (ROSs) affect the resistance of ovarian cancer cells to chemotherapy on the example of cisplatin—an antitumor drug used to ...
Biochemistry
Sep 13, 2018
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12
Ovarian cancer devastates more than 20,000 women in the U.S. every year, due in part to its tendency to evade detection and present after metastatic spread. A key element to slowing metastasis is understanding the mechanisms ...
Cell & Microbiology
Aug 3, 2021
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284
A new anticancer agent developed by the University of Warwick has been studied using microfocus synchrotron X-ray fluorescence (SXRF) at I18 at Diamond Light Source. As described in the Journal of Inorganic Biochemistry, ...
Biochemistry
Jun 19, 2018
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28
The day when an ovarian cancer patient can treat her tumor with a single, painless pill instead of a toxic drug cocktail is the ultimate goal of the pioneering research of a University of Houston (UH) scientist.
Biochemistry
Dec 21, 2010
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0
Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible. In the journal Angewandte Chemie, a research team has now described how a very low dose ...
Biochemistry
Oct 12, 2022
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44
