Nanotechnology offers powerful new possibilities for targeted cancer therapies, but the design challenges are many. Northwestern University scientists now are the first to develop a simple but specialized nanoparticle that ...
Bio & Medicine
Apr 5, 2012
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(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...
Biotechnology
Feb 20, 2012
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One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University ...
Bio & Medicine
Jan 20, 2012
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(PhysOrg.com) -- With the advent of targeted drug therapy for treating cancer, it has become clear that an important predictor of success of these therapies is whether such a drug is reaching its target in the patient. The ...
Bio & Medicine
Nov 21, 2011
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Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, ...
Cell & Microbiology
Sep 15, 2011
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A common chemotherapy drug has been successfully delivered to cancer cells inside tiny microparticles using a method inspired by our knowledge of how the human immune system works. The drug, delivered in this way, reduced ...
Biotechnology
Sep 12, 2011
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(PhysOrg.com) -- A UNC-led study has shown the potential for nanotechnology therapy for ovarian cancer. Scientists at UNC Lineberger Comprehensive Cancer Center and Duke University Medical Center conducted a preclinical study ...
Bio & Medicine
Aug 31, 2011
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Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical ...
Bio & Medicine
Jul 5, 2011
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Measuring the mechanical strength of cancer cell mucus layers provides clues about better ways to treat cancer, and also suggests why some cancer cells are more resistant to drugs than others, according to Kai-tak Wan, associate ...
General Physics
Mar 16, 2011
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A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem ...
Biochemistry
Jan 31, 2011
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