The beginning is the end: How promoters predefine where genes end

Each gene in our DNA has a beginning and an end. Defining the gene's extremities properly is crucial in producing functional protein. Much research has been done to identify what determines when, where, and at which site ...

Simple but revolutionary modular organoids created with hydrogels

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without ...

Stem cell-derived organoids mimic human parathyroid tissue

Patient-derived parathyroid organoids (PTOs) could pave the way for future physiology studies and drug-screening applications, as shown in a study published on October 27 in the journal Stem Cell Reports.

Fully mature hair follicles grown in cultures

A team of researchers from Japan studying the processes of hair follicle growth and hair pigmentation has successfully generated hair follicles in cultures. Their in vitro hair follicle model adds to the understanding of ...

Making lab-grown brain organoids 'brainier'

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people. But not all ...

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