To be or not to be: An organoid

Mini-organs, or organoids, play a big role in the future of medicine. Their countless applications can help develop and implement tailored therapies for each patient. The revolutionary development of organoids started in ...

Organoids produce embryonic heart

There was a time when the idea of growing organs in the lab was the stuff of science fiction. Today, stem cell biology and tissue engineering are turning fiction into reality with the advent of organoids: tiny lab-grown tissues ...

Intestinal regeneration: Lessons from organoid research

The last decade has seen a boom in the field of organoids, miniature organs grown from stem cells in vitro. These systems recapitulate the cell type composition and numerous functions of parent organs—such as brain, kidney, ...

New 3-D cultured cells mimic the progress of NASH

A research team led by scientists from Tokyo University of Agriculture and Technology (TUAT), Japan, has successfully established 3-D cultured tissue that mimics liver fibrosis, a key characteristic of non-alcoholic steatohepatitis ...

CRISPR-HOT: A new tool to 'color' specific genes and cells

Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used this new method, called CRISPR-HOT, to investigate ...

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