People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
0
20
Methamphetamine (meth) abuse is a major health concern. Understanding how meth interacts with its target proteins is crucial for the development of novel medications to address drug addiction. Previous research into the mechanism ...
Biochemistry
Nov 24, 2023
0
53
In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring ...
Molecular & Computational biology
Jan 12, 2023
0
24
Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020—more than five times the number of deaths in the ...
Biochemistry
Dec 15, 2022
0
425
In the past few years, opioids and cannabinoids have received a great deal of attention from the media and public health authorities.
Veterinary medicine
Jul 8, 2021
0
3
Opioids are the most powerful painkillers we have, but they're incredibly addictive.
Other
May 6, 2021
0
7
As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, Ph.D., has been working on new therapeutic interventions that may be able to prevent the bulk ...
Biochemistry
Feb 4, 2021
1
653
Nearly 500,000 people in the U.S. during the past 20 years have died from an opioid overdose. Millions of others—many of them parents—are using, incarcerated or in drug rehabilitation programs. While the drug crisis has ...
Economics & Business
Aug 12, 2020
1
25
Every day, the headlines offer yet another example of how the ongoing opioid epidemic is devastating communities and individual lives. But given the significant role popular media plays in shaping public perceptions, where ...
Social Sciences
Nov 15, 2019
0
9
The U.S. opioid epidemic is being driven by an unprecedented surge in deaths from fentanyl and other synthetic opiates. Fentanyl's powerful effects are long-lasting, and even tiny amounts of the drug can lead to an overdose. ...
Bio & Medicine
Mar 31, 2019
1
238
