Making sense of antisense gene silencing

Gene silencing therapies are used to interfere with, or 'silence', the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies ...

New method for producing synthetic DNA

Chemically synthesized short DNA sequences are extremely important ingredients with countless uses in research laboratories, hospitals, and in industry, like in the method for identifying COVID-19. Phosphoramidites are necessary ...

DropSynth, a one-pot approach to gene synthesis

A team of researchers at the University of California has found a way to synthesize multiple genes from a group of microarray-generated oligonucleotides. In their paper published in the journal Science, the group describes ...

New method for mass-producing high-quality DNA molecules

A new method of manufacturing short, single-stranded DNA molecules can solve many of the problems associated with current production methods. The new method, which is described in the scientific periodical Nature Methods, ...

New research tool targets microRNA expression in zebrafish

A new research tool for studying microRNA expression in zebrafish will help researchers study the effects of miRNA on the early development of this model organism and better understand developmental and disease mechanisms ...

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