A new study in the field of biophysics has revealed how large molecules are able to enter the nucleus of a cell. A team led by Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU) has thus provided important ...
Cell & Microbiology
Aug 24, 2020
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7
In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing ...
Cell & Microbiology
Jul 6, 2020
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3
In a study published online in Science China Life Sciences on May 15, ZHANG Xian-En's team from Institute of Biophysics of the Chinese Academy of Sciences and collaborators discovered how HIV-1 viral cores can enter the nucleus. ...
Cell & Microbiology
May 15, 2020
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A study has solved a long-standing debate about the transport of essential proteins, implicated in many human diseases, through one of the cell's most complex and sophisticated structures.
Molecular & Computational biology
May 4, 2020
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255
An interdisciplinary team from the University of Basel in Switzerland has succeeded in creating a direct path for artificial nanocontainers to enter into the nucleus of living cells. To this end, they produced biocompatible ...
Bio & Medicine
Jan 27, 2020
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462
Barely visible material that looks like tiny grains of sand may hold the key to removing an invisible health threat that has contaminated water supplies across the country. Researchers at Pacific Northwest National Laboratory ...
Materials Science
Jul 10, 2019
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25
In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...
Cell & Microbiology
Jun 12, 2019
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3
If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren't necessarily better: some cancer cells contain a dramatic excess of nuclear pores.
Cell & Microbiology
Sep 19, 2018
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57
Standing guard between a cell's nucleus and its main chamber, called the cytoplasm, are thousands of behemoth protein structures called nuclear pore complexes, or NPCs. NPCs are like the bouncers of a cell's nucleus, tightly ...
Cell & Microbiology
Jun 13, 2018
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119
Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert ...
Biochemistry
Mar 27, 2018
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183
