A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be ...
Cell & Microbiology
Jun 28, 2018
0
58
When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins ...
Bio & Medicine
Dec 6, 2017
0
66
All creatures of the animal kingdom share one thing: the nuclear membrane. Wrapping the genetic core of the cell, this membrane, together with all the attached proteins, plays a vital role in biological functions. Despite ...
Cell & Microbiology
Sep 8, 2017
0
5
Every one of our cells stores its genome within the nucleus – the quintessential subcellular structure that distinguishes eukaryotic cells from bacteria. When animal cells divide, they disassemble their nucleus, releasing ...
Cell & Microbiology
Aug 28, 2017
0
156
Over a century since scientists first observed that cells and their nuclei grow at a constant ratio to each other, researchers are now closer to finding out how.
Cell & Microbiology
Jul 11, 2017
0
1
(Phys.org)—If asked to describe the differences between humans and frogs, a child might say that one hops and rib-its while the other walks and talks. If we ask that same child how to build a frog, they will probably need ...
A smiling and very green Kermit looking down from a wall portrait seems to happily give a thumbs—or flipper—up to one of the University of Wyoming's self-described frog guys trying to unravel the mysteries of what in ...
Biochemistry
Dec 11, 2015
0
8
Susan Gasser and her group at the FMI have identified in C. elegans a much sought-for anchor protein, a previously uncharacterized chromodomain protein called CEC-4 that directly sequesters inactive chromatin at the nuclear ...
Cell & Microbiology
Dec 2, 2015
0
409
Scientists have found a new function of the nuclear membrane, the envelope that encases and protects DNA in the nucleus of a cell - it fixes potentially fatal breaks in DNA strands.
Cell & Microbiology
Oct 29, 2015
9
3148
Nuclear membranes protect genes—life's most precious cargo—but little is known about why they function in different tissue types. For instance, nuclei in brain cells tend to be soft and pliable while those in bone cells ...
Cell & Microbiology
Jun 16, 2015
0
26
