The brains of all higher-order animals are filled with a diverse array of neuron types, with specific shapes and functions. Yet, when these brains form during embryonic development, there is initially only a small pool of ...
Cell & Microbiology
Nov 29, 2022
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100
A research group led by Prof. Hiroyasu Nakano at the Department of Biochemistry, Toho University Faculty of Medicine, identified Mind bomb-2 (MIB2) as an enzyme that ubiquitinates and modifies the protein cFLIP, which plays ...
Cell & Microbiology
Jan 27, 2021
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5
"The winner takes it all, the loser standing small"—that's not just true in the famous ABBA song, but also in animal development. Frequently, a group of cells starts out all being the same. But then one cell puts the brake ...
Cell & Microbiology
Feb 15, 2019
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5
In the womb, our strong spines start as nothing more than a rope of rubbery tissue. As our bodies develop, this flexible cord, called the notochord, morphs into a column of bone and cartilage sturdy enough to hold up our ...
Cell & Microbiology
Feb 22, 2018
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5
Multicellular organisms like ourselves depend on a constant flow of information between cells, coordinating their activities in order to proliferate and differentiate. Deciphering the language of intercellular communication ...
Cell & Microbiology
Feb 16, 2018
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Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first ...
Biochemistry
Jul 18, 2016
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91
University of Oregon scientists studying neural stem cells in the fruit fly Drosophila have uncovered a molecular change experienced by stem cells as they age. During development of the central nervous system, a protein is ...
Cell & Microbiology
Dec 7, 2015
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45
The Notch signaling pathway helps determine cell fate determination, differentiation and proliferative ability of numerous cells. How it accomplishes these tasks has been a puzzle, but researchers led by those at Baylor College ...
Cell & Microbiology
Nov 29, 2012
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(Phys.org)—A new way to visualize single-cell activity in living zebrafish embryos has allowed scientists to clarify how cells line up in the right place at the right time to receive signals about the next phase of their ...
Cell & Microbiology
Nov 13, 2012
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0
As they develop, vertebrate embryos form vertebrae in a sequential, time-controlled way. Scientists have determined previously that this process of body segmentation is controlled by a kind of "clock," regulated by the oscillating ...
Cell & Microbiology
Nov 13, 2012
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