Researchers at the UZH Center for Dental Medicine have investigated the importance of the Notch pathway for the evolution of tooth morphology. Mutations in this signaling pathway can lead to defective structures in tooth ...
Evolution
Jun 27, 2023
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Stem cells are one of the few cell types within the body that have the ability to both self-renew and produce cells that develop into more specialized cell types which eventually built up a functional organ. During development, ...
Cell & Microbiology
Feb 15, 2022
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4
A research group led by Prof. Hiroyasu Nakano at the Department of Biochemistry, Toho University Faculty of Medicine, identified Mind bomb-2 (MIB2) as an enzyme that ubiquitinates and modifies the protein cFLIP, which plays ...
Cell & Microbiology
Jan 27, 2021
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5
Multicellular organisms like ourselves depend on a constant flow of information between cells, coordinating their activities in order to proliferate and differentiate. Deciphering the language of intercellular communication ...
Cell & Microbiology
Feb 16, 2018
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The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how ...
Biochemistry
Sep 15, 2017
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8
When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.
Cell & Microbiology
Oct 31, 2015
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60
The Notch signaling pathway helps determine cell fate determination, differentiation and proliferative ability of numerous cells. How it accomplishes these tasks has been a puzzle, but researchers led by those at Baylor College ...
Cell & Microbiology
Nov 29, 2012
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0
As they develop, vertebrate embryos form vertebrae in a sequential, time-controlled way. Scientists have determined previously that this process of body segmentation is controlled by a kind of "clock," regulated by the oscillating ...
Cell & Microbiology
Nov 13, 2012
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(Phys.org)—A new way to visualize single-cell activity in living zebrafish embryos has allowed scientists to clarify how cells line up in the right place at the right time to receive signals about the next phase of their ...
Cell & Microbiology
Nov 13, 2012
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0
Researchers at Duke University Medical Center have found out how mouse basal cells that line airways "decide" to become one of two types of cells that assist in airway-clearing duties. The findings could help provide new ...
Cell & Microbiology
Jun 17, 2011
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