Biochip advances enable next-generation sequencing technologies

Biochips are essentially tiny laboratories designed to function inside living organisms, and they are driving next-generation DNA sequencing technologies. This powerful combination is capable of solving unique and important ...

How big data is changing science

"This is when I start feeling my age," says Anne Corcoran. She's a scientist at the Babraham Institute, a human biology research centre in Cambridge, UK. Corcoran leads a group that looks at how our genomes – the DNA coiled ...

Faster diagnosis of sepsis pathogens

Microbial pathogens can be diagnosed unambiguously and within just 24 hours by means of high-throughput sequencing of their genetic makeup and special bioinformatics evaluation algorithms. Fraunhofer researchers have validated ...

Improving accuracy in genomic mapping with time-series data

If you already have the sequenced map of an organism's genome but want to look for structural oddities in a sample, you can check the genomic barcode—a series of distances between known, targeted sites—by cutting a DNA ...

Simplifying SNP discovery in the cotton genome

The term "single-nucleotide polymorphism" (SNP) refers to a single base change in DNA sequence between two individuals. SNPs are the most common type of genetic variation in plant and animal genomes and are, thus, an important ...

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