Key enzymes for synthesizing natural products

Plants, fungi and bacteria produce natural products that function as defenses that are deployed against predators and competitors. In medicine, these compounds have such applications as antibiotics, cancer drugs and cholesterol ...

Direct cloning method CAPTUREs novel microbial natural products

Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications. However, many uncharacterized microbial BGCs remain ...

St. John's Wort flowers serve as green catalyst

Since ancient times, St. John's Wort has been used as a medicinal herb covering a wide range of applications such as the treatment of burns, skin injuries, neuralgia, fibrosis, sciatica and depression. Due to its high medicinal ...

Animal venoms as natural resource for new drugs

Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of ...

Covid and commercial research decline

Inevitably, the rapid spread of an emergent and potentially lethal virus around the world has led to huge disruption of normal life. With talk of a new-normal in the wake of the COVID-19 pandemic, we do not yet have any way ...

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