Construction kit for custom-designed products

Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now ...

An unnatural way to make natural products

From medicine to fragrances, nature provides many of the key chemical compounds needed in an endless number of pharmaceuticals and consumer products. Now, a cutting-edge technique engineered by researchers at University of ...

Learning from nature's bounty: New libraries for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...

Grassland areas should be chosen wisely

When farmland is converted from grain production to grasslands, the greatest environmental benefits are obtained by choosing land that is close to existing natural areas or has high nutritional loads to aquatic environments, ...

Measuring methane from coal and gas in Pennsylvania informative

While methane pollution caused by natural gas production in Pennsylvania is underestimated by the U.S. Environmental Protection Agency, natural gas still has half the carbon footprint of underground coal mining, according ...

Engineered microbial production of grape flavoring

Researchers report a microbial method for producing an artificial grape flavor. Methyl anthranilate (MANT) is a common grape flavoring and odorant compound currently produced through a petroleum-based process that uses large ...

Producing food while preserving biodiversity

In nature conservation and agriculture, there are two opposing views of how to combine high biodiversity and sustainable food production: Nature conservation should either be integrated into agricultural land, or segregated ...

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