Genes that dance to the circadian rhythm

Scientists at EPFL have made breakthrough discoveries on the circadian clock and how it affects gene expression. Some of the findings suggest a biological underpinning for different behaviors in people, such as morning people, ...

Quick and sensitive identification of multidrug-resistant germs

Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria. The system is based on tiny, functionalized cantilevers that bend ...

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

Lab tests show risks of using CRISPR gene editing on embryos

A lab experiment aimed at fixing defective DNA in human embryos shows what can go wrong with this type of gene editing and why leading scientists say it's too unsafe to try. In more than half of the cases, the editing caused ...

Yeast study yields insights into longstanding evolution debate

In the past two decades, researchers have shown that biological traits in both species and individual cells can be shaped by the environment and inherited even without gene mutations, an outcome that contradicts one of the ...

Microbial genetics: A protean pathogen

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable. A new study by researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich explores the role played by ...

Barcoding long DNA quantifies CRISPR effects

Current sequencing techniques lack the sensitivity to detect rare gene mutations in a pool of cells, which is particularly important, for example, in early cancer detection. Now, scientists at KAUST have developed an approach, ...

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