News tagged with mutant cells

M6P deficiency leaves B cells out of sorts

A group of white blood cells known as B cells, which play a key role in the human immune response, need a protein-targeting signal called mannose 6-phosphate (M6P) in order to proliferate, differentiate, and present immune ...

dateJan 19, 2015 in Cell & Microbiology
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Self-sorting cells disrupt development

In a developing embryo, some cells can self-segregate – like oil separating out of water – to help create the tissues and organs of the human body. For example, brain cells separate into clusters that give rise to different ...

dateOct 20, 2016 in Cell & Microbiology
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Glycosylation—mapping uncharted territory

Whereas major inroads have been made into genomics, metabolomics, or protein and lipid research, glycosylation remains largely unexplored at the proteome scale. There are limited technologies for profiling the complex glycoproteome. ...

dateSep 21, 2017 in Cell & Microbiology
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Negative feedback makes cells 'sensitive'

New research has shown that negative feedback loops in cell signalling systems can be essential for a cell's ability to perceive the strength of a growth stimulus. Cells lacking the feedback loop became insensitive to the ...

dateJan 08, 2014 in Cell & Microbiology
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