Related topics: stem cells · cancer cells · cells · immune cells · animal model

Genome editing: Efficient CRISPR experiments in mouse cells

In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the ...

Iron nanoparticles make immune cells attack cancer

Stanford researchers accidentally discovered that iron nanoparticles invented for anemia treatment have another use: triggering the immune system's ability to destroy tumor cells.

Why cancer drugs can't take the pressure

A major reason why cancer drugs fail is that they cannot penetrate the high-pressure environment of solid tumors. A study published May 10th in Biophysical Journal reveals that a large, naturally occurring molecule called ...

Better mouse model enables colon cancer research

Every day, it seems, someone in some lab is "curing cancer." Well, it's easy to kill cancer cells in a lab, but in a human, it's a lot more complicated, which is why nearly all cancer drugs fail clinical trials.

Nano packages for anti-cancer drug delivery

Cancer stem cells are resistant to chemotherapy and consequently tend to remain in the body even after a course of treatment has finished, where they can often trigger cancer recurrence or metastasis. A new study by researchers ...

Research team implants human innate immune cells in mice

(Phys.org) —Overcoming a major limitation to the study of the origins and progress of human disease, Yale researchers report that they have transplanted human innate immune cells into mouse models, which resulted in human ...

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