Assembly theory could spell good news for drug discovery
A new method of exploring chemical space could help create scientific breakthroughs in areas including drug design and discovery, its creators say.
A new method of exploring chemical space could help create scientific breakthroughs in areas including drug design and discovery, its creators say.
Biochemistry
Sep 27, 2021
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94
Deep learning has radically changed the field of artificial intelligence. Now neural networks are revolutionizing the way that we discover new drugs. We talk to Francesca Grisoni, assistant professor at the department of ...
Biotechnology
Sep 16, 2021
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240
Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect ...
Biotechnology
Jul 7, 2021
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31
Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope—without affecting their ...
Biochemistry
Jun 30, 2021
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128
When something is awry with your immune system, your digestion or your endocrine systems, nuclear receptors, as they are called, may well be involved. If need be, the operation of these regulator proteins can be altered with ...
Biochemistry
Jun 22, 2021
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9
In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...
Molecular & Computational biology
Jun 1, 2021
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12
The discovery and development of new small-molecule compounds for therapeutic use involves a huge investment of time, effort and resources. Giving a new spin to conventional chemical synthesis, a team of researchers from ...
Other
Jun 1, 2021
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15
A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability—a vital step in the development of new medicines—is being rolled out by scientists from ...
Biochemistry
May 27, 2021
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8
Scientists from the UK's University of Bath explore racemases—an important type of enzyme that is linked to certain cancers and other life-threatening diseases while also being critical to cell function—in a paper published ...
Biochemistry
May 25, 2021
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23
Most drugs are small. But large molecules could be enormously useful medicines—if we could only get them inside our cells. Now, a group of researchers in biomedical engineering—a shared department with the UConn School ...
Biotechnology
May 17, 2021
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13