Researchers reveal DNA repair mechanism

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

Structural insight into process of gene regulation

In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes ...

Filming proteins in motion to understand their functions

Proteins are the heavy-lifters of biochemistry. These beefy molecules act as building blocks, receptors, processors, couriers and catalysts. "Proteins are the molecular machines that power all life on Earth," explained Mark ...

Locking and unlocking molecular structures on demand

Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned—a discovery that may lead to ...

A molecular machine's secret weapon exposed

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have been launched that are dedicated to ...

Unraveling the protein map of the cell's mitochondria

Mitochondria are responsible for the energy supply of the organism and fulfill functions in metabolic and signaling processes. Researchers at the University Hospital Bonn (UKB) and the University of Freiburg have gained systematic ...

New chemistry toolkit speeds analyses of molecules in solution

A new open-source toolkit automates the process of computing molecular properties in the solution phase, clearing new pathways for artificial-intelligence design and discovery in chemistry and beyond. The Journal of Chemical ...

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