Breakthrough discovery in mitochondrial regulation

Researchers from Osaka University identify a system known as the "GET pathway" as essential for efficient regulation of the numbers of energy-producing mitochondria

Formation of pores in mitochondrial membrane elucidated

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40% of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important ...

Study investigates crosstalk between mitochondria and lysosomes

Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, according to a Northwestern Medicine study published in the Journal of Cell Biology. These findings ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

Research team first to develop 3D structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...

page 2 from 7