A ribosome odyssey in mitochondria

Proteins make life and are made by ribosomes. In mitochondria, the repertoire of the mitoribosomal architectures turns out to be much more diverse than previously thought.

Lysosome to mitochondria communication regulates longevity

As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, ...

Mitochondrial distress signaling pathway revealed in new study

Mitochondria cannot autonomously cope with stress and must instead call on the cell for help. Molecular geneticists at LMU have identified the long-sought signaling pathway which enables the organelles to do so.

Strategy to help cells get rid of disease-related debris

Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. Further research could lead to treatments for neurodegenerative and metabolic diseases, Down syndrome, and maybe ...

New research tool for studying mitochondrial disorders and aging

Researchers at Karolinska Institutet in Sweden have developed a new research tool for studying how mitochondrial protein synthesis is affected by disease, pharmaceuticals, aging and different physiological situations such ...

Protein quality control and mitochondria

Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...

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