Protein quality control and mitochondria

Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...

Anti-aging molecule NAD+ gets a boost from blocking an enzyme

Nicotinamide adenine dinucleotide (NAD+) is a major player in nutrition today. Studies have shown that NAD+ concentrations decrease during aging and that recovering the body's levels of NAD+ can prolong both health span and ...

Cells stressed out? Make mitochondria longer

Scientists at The Scripps Research Institute (TSRI) have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

Researchers discover mitochondria-to-nucleus messenger protein

Researchers have identified a protein, G-Protein Pathway Suppressor 2 (GPS2), that moves from a cell's mitochondria to its nucleus in response to stress and during the differentiation of fat cells. While proteins with similar ...

Surprise! This eukaryote completely lacks mitochondria

Mitochondria are membrane-bound components within cells that are often described as the cells' powerhouses. They've long been considered as essential components for life in eukaryotes, the group including plants, fungi, animals, ...

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