New technique developed for targeted protein degradation

A new study published in Nature Communications from researchers at Karolinska Institutet solves a long-standing problem by establishing a system that allows site-specific protein degradation within mitochondria, the cellular ...

Muscle health depends on lipid synthesis, shows study

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers at the Institute of Molecular Biotechnology ...

Two hits to the mitochondria can cause severe anemia

Mitochondria may seem like small cogs in the complex machinery of the cell, but even little gears can drive big changes. Now, researchers from Japan have found that impairing mitochondria in two different ways can have a ...

New aging-related molecular pathway discovered

A collaborative project between the labs of Maulik Patel, assistant professor of biological sciences, and Kris Burkewitz, assistant professor of cell and developmental biology, has identified a new molecular pathway that ...

Key amino acid in heme production helps fight aging in muscles

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid (5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading ...

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