Targeting an RNA-binding protein to fight aging

Aging bodies undergo biological changes that cause a decline in the function of cells and tissues. However, most studies attempting to identify molecules involved in age-related dysfunctions have focused only on mechanisms ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Strategy to help cells get rid of disease-related debris

Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. Further research could lead to treatments for neurodegenerative and metabolic diseases, Down syndrome, and maybe ...

How heart failure disrupts the cell's mitochondria

Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising ...

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