Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Strategy to help cells get rid of disease-related debris

Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. Further research could lead to treatments for neurodegenerative and metabolic diseases, Down syndrome, and maybe ...

Targeting an RNA-binding protein to fight aging

Aging bodies undergo biological changes that cause a decline in the function of cells and tissues. However, most studies attempting to identify molecules involved in age-related dysfunctions have focused only on mechanisms ...

Cells stressed out? Make mitochondria longer

Scientists at The Scripps Research Institute (TSRI) have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

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