New insights into mitochondrial nucleoid dynamics

Mitochondria are important cellular structures that are vital for their role in generating energy. Mitochondria are dynamic, meaning they constantly fuse together and split apart. They contain a small amount of genetic information ...

How heart failure disrupts the cell's mitochondria

Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising ...

Small proteins play big role in cellular energy balance

Scientists at Duke-NUS Medical School have discovered new molecular details of how cells ensure that their energy supply is adjusted to meet energy demand. Their study, carried out in collaboration with researchers at the ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

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