New technique developed for targeted protein degradation

A new study published in Nature Communications from researchers at Karolinska Institutet solves a long-standing problem by establishing a system that allows site-specific protein degradation within mitochondria, the cellular ...

Uncovering hidden mitochondrial mutations in single cells

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...

Muscle health depends on lipid synthesis, shows study

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers at the Institute of Molecular Biotechnology ...

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