Related topics: cells

Centriole instability might contribute to some cases of microcephaly

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...

First evidence of microtubules' mechanosensitive behavior

Inside cells, microtubules not only serve as a component of the cytoskeleton (cell skeleton) but also play a role in intracellular transport. In intracellular transport, microtubules act as rails for motor proteins such as ...

Strengthened microtubules aid cell migration

Migrating cells use stiffened microtubules to push through tissue barriers, seeking out weak points in tissue, according to a Northwestern Medicine study published in Cell Reports.

Stronger together: How protein filaments interact

Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilized and moved by a cellular skeleton. Unlike the vertebrate skeleton, this cellular skeleton is a very dynamic ...

Tracking proteins in the heart of cells

Cells must provide their internal organelles with all the energy elements they need, which are formed in the Golgi apparatus, the center of maturation and redistribution of lipids and proteins. But how do the proteins that ...

Dewdrops on a spiderweb reveal the physics behind cell structures

As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon ...

Keeping sperm cells on track

An essential component of every eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells. Cilia and flagella, which are antenna-like structures ...

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Microtubule

Microtubules are a component of the cytoskeleton. These rope-like polymers of tubulin can grow as long as 25 micrometers and are highly dynamic. The outer diameter of microtubule is about 25 nm. Microtubules are important for maintaining cell structure, providing platforms for intracellular transport, forming the spindle during mitosis, as well as other cellular processes. There are many proteins that bind to the microtubule, including motor proteins such as kinesin and dynein, severing proteins like katanin, and other proteins important for regulating microtubule dynamics.

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