Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment. During cell division, for instance, these cables latch onto chromosomes and ...
Cell & Microbiology
May 1, 2023
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In a multidisciplinary study newly published in the Journal of Cell Biology, the Barral group (D-BIOL/IBC) together with the Steinmetz group (PSI) and the Stelling group (D-BSSE), sheds light on how the motor domain of the ...
Cell & Microbiology
Apr 28, 2023
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Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare the cell for cell ...
Cell & Microbiology
Mar 9, 2023
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Researchers led by Dr. Jens Lüders at IRB Barcelona have discovered a key role played by the ch-TOG protein in the initiation of microtubule assembly during the interphase stage of the cell cycle—the phase in which cells ...
Cell & Microbiology
Jan 26, 2023
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Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers from the Okayama University reported that microtubules are ...
Cell & Microbiology
Jan 18, 2023
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Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue. Clinging to the ends of filaments called microtubules, ...
Cell & Microbiology
Dec 19, 2022
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To make new cells, we have to divide existing ones. This is a continuous, frequent and ubiquitous process which starts at conception and ends at death. There are an estimated 37 trillion cells in the tissues and organs of ...
Cell & Microbiology
Nov 28, 2022
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Propofol is the most commonly used drug to induce general anesthesia. Despite its frequent clinical application, exactly how propofol causes anesthesia is poorly understood.
Cell & Microbiology
Nov 7, 2022
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The tau protein is an important factor linked to the development of human neurodegenerative diseases, including Alzheimer's disease. Yet there is still much we do not know about tau and other similar proteins. The most recent ...
Cell & Microbiology
Aug 23, 2022
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Understanding the busy networks inside our cells can help researchers develop new cancer treatments and prevent dangerous fungal infections.
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Aug 9, 2022
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Microtubules are a component of the cytoskeleton. These rope-like polymers of tubulin can grow as long as 25 micrometers and are highly dynamic. The outer diameter of microtubule is about 25 nm. Microtubules are important for maintaining cell structure, providing platforms for intracellular transport, forming the spindle during mitosis, as well as other cellular processes. There are many proteins that bind to the microtubule, including motor proteins such as kinesin and dynein, severing proteins like katanin, and other proteins important for regulating microtubule dynamics.
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