Exploring flow transport in egg cells

Northwestern Medicine scientists discovered a new and unique transport mechanism within developing egg cells in fruit flies, according to a study published in eLife.

Centriole instability might contribute to some cases of microcephaly

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole ...

First evidence of microtubules' mechanosensitive behavior

Inside cells, microtubules not only serve as a component of the cytoskeleton (cell skeleton) but also play a role in intracellular transport. In intracellular transport, microtubules act as rails for motor proteins such as ...

Strengthened microtubules aid cell migration

Migrating cells use stiffened microtubules to push through tissue barriers, seeking out weak points in tissue, according to a Northwestern Medicine study published in Cell Reports.

Stronger together: How protein filaments interact

Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilized and moved by a cellular skeleton. Unlike the vertebrate skeleton, this cellular skeleton is a very dynamic ...

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