Team decodes another piece of the histone code puzzle

Inside our cells, DNA is tightly packed and spooled around proteins called histones. Packaging DNA in this way allows large amounts of genetic material to exist inside the cell in a final form called chromatin. Tiny enzymes ...

A genome-scale map of DNA methylation kinetics

While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...

'Living fossil' may upend basic tenet of evolutionary theory

The field of evolutionary biology has seen its share of spirited debates. But if there's one principle that virtually every expert in the field agrees on, it's that natural selection occurs at the level of the genome.

Method to customize microbes for better biofuel production

Scientists at the US Department of Energy's Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating ...

Scientists uncover mystery of DNA methylation

All species mark their DNA with methyl groups. This is done to regulate gene expression, distinguish indigenous DNA from foreign DNA, or to mark old DNA strands during replication. Methylation is carried out by certain enzymes ...

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