New chemistry makes 'magic' drug improvements easier
In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.
In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.
Biochemistry
Apr 23, 2021
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A team of researchers from a number of institutions in the U.S. has identified a DNA methylation regulator called QSER1. In their paper published in the journal Science, the group describes studying the valleys of unmethylated ...
Researchers at GMI—Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences—have uncovered an ingenious mechanism by which Arabidopsis safeguards the integrity of its genome. The paper is ...
Cell & Microbiology
Apr 8, 2021
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31
Bacterial DNA methylation occurs in diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has ...
Biotechnology
Apr 5, 2021
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It has long been understood that a parent's DNA is the principal determinant of health and disease in offspring. Yet inheritance via DNA is only part of the story; a father's lifestyle such as diet, being overweight and stress ...
Molecular & Computational biology
Mar 16, 2021
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The sperm of older rats differs from that of younger rats in ways that may affect embryo development, according to recently published research.
Evolution
Mar 16, 2021
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A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. The study also showed age-related changes to the DNA of long-lived ...
Plants & Animals
Mar 12, 2021
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170
In a colorful solution to a dangerous problem, Australian scientists are adapting a component from cutting-edge solar cells to design a rapid, light-based detection system for deadly toxins.
Nanomaterials
Mar 4, 2021
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36
Going on holiday can affect shift workers on the level of gene function: a new study indicates that resting during a holiday period restored functions associated with DNA regulation in shift workers suffering from sleep deprivation.
Biotechnology
Feb 22, 2021
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103
Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth. Indigenous populations that have lived in these extreme ...
Evolution
Feb 12, 2021
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