New chemistry makes 'magic' drug improvements easier

In the last decade, scientists discovered a quirk of drug chemistry: If you add on a simple one-carbon building block to a drug, it can make the drug more potent, less toxic, or more stable.

DNA methylation regulator QSER1 identified

A team of researchers from a number of institutions in the U.S. has identified a DNA methylation regulator called QSER1. In their paper published in the journal Science, the group describes studying the valleys of unmethylated ...

Lockdown for genome parasites

Researchers at GMI—Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences—have uncovered an ingenious mechanism by which Arabidopsis safeguards the integrity of its genome. The paper is ...

The epigenetics of life at 12,000 feet

Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth. Indigenous populations that have lived in these extreme ...

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