Related topics: cancer · cancer cells · breast cancer · tumor · cells

A revolutionary technology to study cell nanomechanics

Researchers at Singapore-MIT Alliance for Research and Technology (SMART) and MIT's Laser Biomedical Research Center (LBRC) have developed a new way to study cells, paving the way for a better understanding of how cancers ...

A 'switch' that regulates traffic across blood vessels

NUS scientists have discovered a control mechanism that regulates the traffic of cells and substances across blood vessels. This effect can have significant impact on cancer metastasis.

Non-invasive imaging method spots cancer at the molecular level

Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or ...

Can we cure cancer by finding out how two proteins interact?

In a paper published in the Journal of Biological Chemistry, Dr. Özdemir has studied two protein families named Rho GTPases and IQGAPs, which are known to play an important role in cancer metastasis. These two "suspicious" ...

Tumor cell expansion challenges current physics

A malignant tumor is characterized by the ability to spread. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use physical forces to propel themselves. A study published in Nature Physics by a team ...

Engineer develops model to predict behavior of cell clusters

An engineer at Washington University in St. Louis discovered a model in which the mechanics of the cells' environment can predict their movement, a finding that ultimately could mean confining cell transition in tumors and ...

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Metastasis (Greek: displacement, μετά=next + στάσις=placement, plural: metastases), or Metastatic disease, sometimes abbreviated mets, is the spread of a disease from one organ or part to another non-adjacent organ or part. Only malignant tumor cells and infections have the established capacity to metastasize; however, this is recently reconsidered by new research.

Cancer cells can break away, leak, or spill from a primary tumor, enter lymphatic and blood vessels, circulate through the bloodstream, and settle down to grow within normal tissues elsewhere in the body. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most tumors and other neoplasms can metastasize, although in varying degrees (e.g., glioma and basal cell carcinoma rarely metastasize).

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are like those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.

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