CasPER—a new method for diversification of enzymes

A new study published in the Metabolic Engineering Journal describes a method based on CRISPR/Cas9, which enables flexible engineering of essential and nonessential enzymes without additional engineering. This has multiple ...

Measuring metabolites in algae one cell at a time

In the search for new sources of consumables, scientists have come to realize that life itself could be the solution. Metabolic engineers have altered the metabolism of living organisms to make new drugs, biodegradables and ...

A new way to do metabolic engineering

A novel method developed by a group of researchers at the Carl R. Woese Institute for Genomic Biology (IGB) at the University of Illinois could change the way metabolic engineering is done.

Microbes could make drug production more efficient

Alkaloid-based pharmaceuticals derived from plants can be potent treatments for a variety of illnesses. But getting these powerful therapeutic agents from plants can take a long time and cost plenty of money, because it often ...

Performing cellular surgery with a laser-powered nanoblade

To study certain aspects of cells, researchers need the ability to take the innards out, manipulate them, and put them back. Options for this kind of work are limited, but researchers reporting May 10 in Cell Metabolism describe ...

Converting E. coli into a pharmaceutical factory

(Phys.org)—Taxol is the most well-known anti-cancer drug, and has proven remarkably effective against a variety of cancers since the 1970s. It's a natural substance, derived from the bark of yew trees, and as such, its ...

Non-natural biomedical polymers produced from microorganisms

Renewable non-food biomass could potentially replace petrochemical raw materials to produce energy sources, useful chemicals, or a vast array of petroleum-based end products such as plastics, lubricants, paints, fertilizers, ...

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