Lipid research may help solve COVID-19 vaccine challenges

New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain COVID-19 vaccines worldwide—the need for the vaccines to be kept at below-freezing temperatures during ...

Inside the protein channel that keeps bacteria alive

Almost all bacteria rely on the same emergency valves—protein channels that pop open under pressure, releasing a deluge of cell contents. It is a last-ditch effort, a failsafe that prevents bacteria from exploding and dying ...

Division and growth of synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism ...

Revealing the way a critical enzyme works in the cell

S-acylation is the process of chemically linking a lipid to protein via a thioester bond. It is an important process of the cell that regulates the localization and function of numerous proteins. It promotes lipid membrane ...

Pore-like proteins designed from scratch

In a milestone for biomolecular design, a team of scientists has succeeded in creating new proteins that adopt one of the most complex folds known to molecular biology. These designer proteins were shown in the lab to spontaneously ...

How cells 'eat' their own fluid components

Autophagy is a fundamental cellular process by which cells capture and degrade their own dysfunctional or superfluous components for degradation and recycling. Recent research has revealed that phase separated droplets have ...

Super-resolution 'street view' microscopy hits the SPOT

The ability to "see" the inner workings of structures (organelles) within cells, in real time, offers the promise of advancements in disease diagnosis and treatment. Organelle dynamics drive the self-efficient micro-world ...

Revealing the identity of the last unknown protein of autophagy

Dr. Nobuo Noda and Dr. Kazuaki Matoba at the Institute of Microbial Chemistry discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) ...

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