Modelling HIV fusion

An interdisciplinary team of researchers at the Indian Institute of Science (IISc) has used robust computer simulations to understand how HIV, the virus that causes AIDS, fuses with the host cell membrane. Published in the ...

Research describes missing step in how cells move their cargo

Every time a hormone is released from a cell, every time a neurotransmitter leaps across a synapse to relay a message from one neuron to another, the cell must undergo exocytosis. This is the process responsible for transporting ...

Team unveils new Leishmania virulence strategies

Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite. These scientific breakthroughs recently published in ...

A long-standing mystery in membrane traffic solved

In 2013, James E. Rothman, Randy W. Schekman, and Thomas C. Südhof won the Nobel Prize in Physiology or Medicine for their discoveries of molecular machineries for vesicle trafficking, a major transport system in cells for ...

Protein recycling machine visualized

Howard Hughes Medical Institute (HHMI) scientists have new structures of an essential cellular recycling machine that depict its structure with near atomic-level detail. The structures, which show a protein called NSF alone ...

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