Related topics: protein

Stellar explosion in Earth's proximity

When the brightness of the star Betelgeuse dropped dramatically a few months ago, some observers suspected an impending supernova—a stellar explosion that could also cause damage on Earth. While Betelgeuse has returned ...

Three Interesting Uses for Mass Spectrometry

( -- When many think about mass spectrometry, they visualize uses in biomolecular work. This is because mass spectrometry used in MALDI and ESI techniques is much less harsh than ionization methods used before. ...

Beewolves protect their offspring with antibiotics

Digger wasps of the genus Philanthus, so-called beewolves, house beneficial bacteria on their cocoons that guarantee protection against harmful microorganisms. Scientists of the Max Planck Institute for Chemical Ecology in ...

Extinct giant ape directly linked to the living orangutan

By using ancient protein sequencing, researchers have retrieved genetic information from a 1.9 million year old extinct, giant primate that used to live in a subtropical area in southern China. The genetic information allows ...

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios. In a typical MS procedure:

MS instruments consist of three modules: an ion source, which can convert gas phase sample molecules into ions (or, in the case of electrospray ionization, move ions that exist in solution into the gas phase); a mass analyzer, which sorts the ions by their masses by applying electromagnetic fields; and a detector, which measures the value of an indicator quantity and thus provides data for calculating the abundances of each ion present. The technique has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation. Other uses include quantifying the amount of a compound in a sample or studying the fundamentals of gas phase ion chemistry (the chemistry of ions and neutrals in a vacuum). MS is now in very common use in analytical laboratories that study physical, chemical, or biological properties of a great variety of compounds.

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