Hepatocyte Growth Factor (HGF) is a protein that acts as a cell growth factor. By binding to its receptor protein MET on the cell membrane, it exerts its physiological functions such as proliferation and migration of cells, ...
Biochemistry
May 29, 2019
0
9
Thanks to our understanding of molecular biology, we have made tremendous progress in medicine, with scientists shedding light on the molecular mechanisms of several diseases. However, despite knowing how these diseases occur ...
Biochemistry
Sep 8, 2021
0
40
A University at Buffalo-led research team has developed molecules that could help unclog thick, sticky mucus from the lungs of people suffering from cystic fibrosis.
Biochemistry
Oct 10, 2023
0
2
A team including researchers from Osaka University has produced a new molecular emitter for organic light-emitting diodes (OLEDs). Using rational chemical design with U-shaped synthetic building blocks, the scientists were ...
Materials Science
Jan 20, 2020
0
21
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...
Biochemistry
Jun 11, 2019
0
3
For us humans, a healthy brain handles all the minute details of bodily motion without demanding conscious attention. Not so for brainless robots – in fact, calculating robotic movement is its own scientific subfield.
Biochemistry
Jan 16, 2018
0
10
Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...
Biochemistry
Feb 22, 2021
0
13
In polymetallic complexes, two or more metal atoms combine with organic molecules into larger, complicated molecular structures. Such complexes are used in the development of e.g. new catalysts, molecular magnets and sensors. ...
Materials Science
Oct 5, 2021
0
26
In a study recently published in the journal Nature Biomedical Engineering, researchers from Kanazawa University use a method called "lasso-grafting" to design therapeutics with enhanced longevity and brain penetration.
Biotechnology
Nov 8, 2022
0
32
There are currently only a few synthetic agents that bind to and block the widespread membrane transport proteins, ATP-binding cassette transporters (ABC). Scientists at Goethe University and the University of Tokyo identified ...
Molecular & Computational biology
May 17, 2021
0
7
