Chemists create the brightest-ever fluorescent materials

By formulating positively charged fluorescent dyes into a new class of materials called small-molecule ionic isolation lattices (SMILES), a compound's brilliant glow can be seamlessly transferred to a solid, crystalline state, ...

Using molecules to draw on quantum materials

Over millennia, civilizations progressed through the Stone, Bronze, and Iron Ages. Now the time has come for quantum materials to change the way we live, thanks in part to research conducted at the Institut National de la ...

Shaping the rings of molecules

Macrocycles are molecules made of large rings of atoms. Despite being relatively big and flexible, the molecules don't always stay "floppy"—they can actually lock themselves into specific shapes and geometries.

Unique organic light-emitting molecular emitters

A team including researchers from Osaka University has produced a new molecular emitter for organic light-emitting diodes (OLEDs). Using rational chemical design with U-shaped synthetic building blocks, the scientists were ...

New cyclization reactions for synthesizing macrocyclic drug leads

Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study is published in Science ...

Learning from nature's bounty: New libraries for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...

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