Pop-up factories beneath the cell membrane

A living cell is exposed to a variety of stimuli. Countless messengers dock on its surface, where receptors in the cell membrane receive the incoming "orders." Signaling cascades are then triggered inside the cell, which ...

Using cold to enhance microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing ...

DNA replication under the microscope

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

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