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Selective synthesis of meta isomers now possible

In a recent study published in Science, four RIKEN organic chemists have come up with a way to selectively synthesize isomers of an important group of aromatic compounds. This promises to make it possible to manufacture chemicals ...

Chemical reaction design goes virtual

Researchers at the Institute for Chemical Reaction Design and Discovery and Hokkaido University have developed a virtual ligand-assisted (VLA) screening method that could drastically reduce the amount of trial and error required ...

Protein structure offers clues to drug-resistance mechanism

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple ...

Understanding how autoactivation triggers cell death

Apoptosis is a process that causes cell death. It can go awry in cancer cells, sustaining the disease. Scientists at St. Jude Children's Research Hospital have captured the structure of BAK, a protein that triggers apoptosis. ...

New route to the synthesis of P-chiral compounds

Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral ...

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