Jekyll and Hyde: motion may explain similar enzymes' divergence
One enzyme regulates the body's insulin receptor, ensuring energy needed for function and survival. The other enables a bacterium to wreak havoc in the form of bubonic plague.
One enzyme regulates the body's insulin receptor, ensuring energy needed for function and survival. The other enables a bacterium to wreak havoc in the form of bubonic plague.
Biochemistry
Aug 22, 2013
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A small, brown mouse found in the forests of Central America bucks the rodent trend of conversing in high-pitched squeaks often inaudible to the human ear.
Plants & Animals
Apr 25, 2018
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According to the World Health Organization, more than two-thirds of Americans are overweight or obese. And it's not just humans who are packing on the pounds. Our furry companions are plagued by an obesity epidemic of their ...
Other
Apr 10, 2013
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Researchers have discovered in fruit flies a key metabolic hormone thought to be the exclusive property of vertebrates. The hormone, leptin, is a nutrient sensor, regulating energy intake and output and ultimately controlling ...
Cell & Microbiology
Sep 27, 2012
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Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic—not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control ...
Cell & Microbiology
Jun 2, 2009
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Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from ...
Cell & Microbiology
Oct 15, 2021
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40
Researchers have found that even a very little bit of the fat hormone leptin goes a long way when it comes to correcting diabetes. The hormone controls the activity of a gene known as IGFBP2 in the liver, which has antidiabetic ...
Cell & Microbiology
Jan 5, 2010
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Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair.
Feb 13, 2009
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(PhysOrg.com) -- The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it ...
Jan 6, 2009
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Mice with increased levels of a natural brain chemical don’t gain weight when fed a high-fat diet, researchers at UT Southwestern Medical Center have found.
Jan 28, 2009
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Leptin (Greek leptos meaning thin) is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The Ob(Lep) gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.
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