Molecule regulating sperm motility discovered

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful. Now, a team ...

Research shows the way to more efficient EPO production

To many people, EPO rhymes with doping and cycling. But in fact, EPO is an important medical drug. This hormone works naturally in the body by stimulating red blood cell production. Patients suffering from anemia caused by ...

Highly efficient CRISPR knock-in in mouse

Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...

Fast track to mouse modeling

What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...

Muscle gene may provide new treatments for obesity and diabetes

(PhysOrg.com) -- Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal ...

Merkel cells revealed as secret behind sensation of light touch

Scientists have proved experimentally what has been suspected since the discovery of Merkel cells in the skin over a century ago: the sense of light touch that is critical for hand dexterity would not be possible without ...

Knockouts in human cells point to pathogenic targets

(PhysOrg.com) -- Whitehead researchers have developed a new approach for genetics in human cells and used this technique to identify specific genes and proteins required for pathogens.

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