During the process of cell division, chromosomes must be distributed equally between the two emerging daughter cells. One copy of each chromosome is created and remains glued to the original until threads, called microtubules, ...
Cell & Microbiology
Sep 9, 2016
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Whitehead Institute researchers have revealed the architecture of a protein complex that plays a foundational role in the machine that directs chromosome segregation during cell division.
Cell & Microbiology
Nov 19, 2015
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(Phys.org) —At the cellular level, the mitotic spindle apparatus is arguably the most complicated piece of machinery in existence. Its basic function is to isolate and separate the chromosomes during cell division. A group ...
In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ...
Cell & Microbiology
Sep 11, 2013
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(Phys.org) —Researchers at Warwick Medical School have identified the key role played by a team of proteins in the process of mitosis. Working out how to control them may give scientists a way to destroy cancerous cells.
Cell & Microbiology
Aug 7, 2013
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Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered ...
Cell & Microbiology
Apr 21, 2013
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(Phys.org) -- With the first-ever three-dimensional image of an isolated kinetochore – the bulky molecular machine that connects a chromosome to the long, thin microtubules that tug it to one end of a dividing cell -- ...
Cell & Microbiology
Aug 21, 2012
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Centromeres are specialised regions of the genome, which can be identified under the microscope as the primary constriction in X-shaped chromosomes. The cell skeleton, which distributes the chromosomes to the two daughter ...
Cell & Microbiology
Nov 3, 2011
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When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell's interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, ...
Cell & Microbiology
Aug 18, 2011
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The protein complex responsible for the distribution of chromosomes during cell division is assembled in the transition regions between heterochromatin and euchromatin.
Cell & Microbiology
Jul 5, 2011
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