Bioengineers have shown great promise in creating complex multicellular kidney organoids (tiny, self-organized tissues) in the lab using pluripotent stem cells . They can further improve the procedure for different outcomes, ...
Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology. Virtually every cell has a primary cilium that functions to ...
Biochemistry
Nov 25, 2019
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32
Cilia, or flagella—whiplike appendages on cells—perform diverse tasks required to keep the body healthy. When cilia malfunction, the consequences can be devastating, causing a range of problems, from blindness, to lung ...
Cell & Microbiology
Nov 22, 2019
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166
Metals such as zinc, copper and chromium bind to and influence a peptide involved in insulin production, according to new work from chemists at the University of California, Davis. The research is part of a new field of "metalloendocrinology" ...
Biochemistry
May 17, 2019
2
133
UW scientists are prepping a kidney-on-a-chip experiment at Cape Canaveral, Florida, awaiting a shuttle launch that will take the chips into space. At an altitude of 250 miles, astronauts will help study how reduced gravity in ...
Space Exploration
Apr 19, 2019
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19
Researchers at Johns Hopkins Medicine have developed a new molecular tool they call EXoO, which decodes where on proteins specific sugars are attached—a possible modification due to disease. The study, published in issue ...
Molecular & Computational biology
Dec 6, 2018
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3
The surfaces of most cell types are covered by hair-like cilia that play critical roles in cell and fluid motility, environment sensing, and cell-cell communication (signalling).
Cell & Microbiology
Oct 15, 2018
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45
Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That's what it's like to sneak a targeted drug into a kidney and keep it ...
Bio & Medicine
Aug 21, 2018
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10
Among the most studied protein machines in history, mTORC1 has long been known to sense whether a cell has enough energy to build the proteins it needs to multiply as part of growth. Because faulty versions of mTORC1 contribute ...
Cell & Microbiology
Jun 21, 2018
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82
Scientists at Johns Hopkins Medicine and the National Tsing Hua University in Taiwan say they have found a fast way to manipulate a cell's cilia, the tiny, fingerlike protrusions that "feel" and sense their microscopic environment. ...
Cell & Microbiology
May 15, 2018
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