Research team identifies key step in process of Shigella infection

Researchers from the Massachusetts General Hospital (MGH) Division of Infectious Diseases are investigating the mechanism by which several important pathogenic species of bacteria deliver proteins into the cells of the organisms ...

Cytoskeletons shaking hands

Animal cells harbor three types of cytoskeletal elements: actin filaments, intermediate filaments and microtubules. Despite their name, cytoskeletons are very dynamic structures, which undergo rapid reorganization in cells ...

Desmoplakin's tail gets the message

Cells control the adhesion protein desmoplakin by modifying the tail end of the protein, and this process goes awry in some patients with arrhythmogenic cardiomyopathy, according to a study in The Journal of Cell Biology.

Research explores road signs on the intracellular highway

The interior of every cell within our bodies is crisscrossed with a network of molecular highways upon which nutrients, replacement parts, and other vital materials travel to their appropriate location. The system is immensely ...

Skeleton key for cancer metastasis

Cancer cells need all three of their cytoskeletons—actin, microtubules, and intermediate filaments—to metastasize, according to a study published online on April 26 in the Journal of Cell Biology.