Prion diseases, such as bovine spongiform encephalopathy ("mad cow disease"), are lethal neurodegenerative infectious diseases that affect humans and other mammals and for which there is currently no cure.
Biochemistry
Sep 19, 2022
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A short segment of an infectious protein known as a prion protein plays a crucial role in determining how susceptible the protein is to interspecies prion transmission, RIKEN researchers have discovered in a yeast study. ...
Cell & Microbiology
Jul 17, 2020
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Infectious prions or PrPSc—misfolded versions of the normal cellular prion protein PrPC—convert their normal counterparts into copies of themselves and thereby cause fatal disease. How this conversion works at the molecular ...
Biochemistry
Sep 8, 2016
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Grass plants can bind, uptake and transport infectious prions, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The research was published online in the latest issue of Cell ...
Cell & Microbiology
May 16, 2015
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Crows fed on prion-infected brains from mice can transmit these infectious agents in their feces and may play a role in the geographic spread of diseases caused by prions, such as chronic wasting disease or scrapie.
Plants & Animals
Oct 17, 2012
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(Phys.org) -- Prions, infectious agents composed of proteins with a specific misfolded and transmissible 3D structure that cuases diseases like BSE, can be present in fungal populations on a large scale, preventing the spread ...
Cell & Microbiology
Jun 19, 2012
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(PhysOrg.com) -- A group of French researchers has found that prions are more easily able to jump between species than has been previously thought. In their paper published in Science, they show that prions from other species, ...
Prions are causing fatal and infectious diseases of the nervous system, such as the mad cow disease (BSE), scrapie in sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz Zentrum München and Technische Universität ...
Biochemistry
Nov 18, 2009
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