Illuminating the dark side of the genome

Almost 50 percent of our genome is made up of highly repetitive DNA, which makes it very difficult to be analysed. In fact, repeats are discarded in most genome-wide studies and thus, insights into this part of the genome ...

New mechanism discovered in meiosis

Inactivated, but still active– how modification of an enzyme governs critical processes in sexual reproduction.

Protein maintains order in the nucleus

Researchers in Freiburg identify a protein responsible for the correct arrangement of the chromosome centromeres in the nucleus.

Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. ...

Chromosome centromeres are inherited epigenetically

Centromeres are specialised regions of the genome, which can be identified under the microscope as the primary constriction in X-shaped chromosomes. The cell skeleton, which distributes the chromosomes to the two daughter ...

New nerve cells -- even in old age

After birth the brain looses many nerve cells and this continues throughout life - most neurons are formed before birth, after which many excess neurons degenerate. However, there are some cells that are still capable of ...

Immunology

Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. Immunology has applications in several disciplines of science, and as such is further divided.

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